USA Contract Manufacturer for Teeth Whitening, Dietary Supplements & Topicals

(626) 380-5887‬ | (714) 858-3097

info@atriumsci.com

10871 Capital Ave

Garden Grove, CA 92843
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(626) 380-5887‬ | (714) 858-3097

info@atriumsci.com

10871 Capital Ave

Garden Grove, CA 92843

ABOUT US

At the Edge of Innovation

Advanced Delivery Systems for Ambitious Projects in the USA

Atrium utilizes advanced polymer science to encapsulate and protect active ingredients, and improve bioavailability.

Who We Are

We are a US-based contract manufacturer that specializes in difficult, multi-component formulations — from professional in-office teeth-whitening systems engineered for summer heat-stability, to sublingual / orodispersible films (ODF) with high active loads, multi-chamber dispensers, suppository delivery systems, and dietary supplement innovations. We combine rapid prototyping, analytical rigor, and design-for-scale manufacturing to move ideas from lab to launch.

Why Customers Choose Us for the “Too Hard” Projects

We formulate with cellulose ethers, crosslinkable acrylates, block copolymers, PEG/lipid matrices, and smart rheology modifiers to tune adhesion, occlusion, and release.

We formulate and design for 50 °C / 122 °F summer shipping, validated by accelerated stability.

Experience with binary systems (e.g., peroxide + activator) in dual-barrels, and two-stage strips.

We have taken prestige beauty, dental, and Amazon-first brands from formulation to commercial scale – successfully launched on Sephora, Ulta, CVS, Amazon, and featured on Good Morning America multiple times.

Our Specialties: Oral-Care | Sublingual Film | Suppository | Dietary Supplement

If you’re expanding your product lines and need a partner who can formulate, scale, and manufacture reliably in the US, you’re in the right place. Atrium Scientific is best fit for: established brands and manufacturers who value Made in USA, cGMP quality systems, and repeatable output.


Quality, Compliance & Manufacturing
at US Scale

Facility: US-based, FDA-registered, cGMP compliant
QA/QC: Incoming, release testing, stability, retain program, CAPA
Packaging: Oxygen and moisture-barrier materials, dual-chambers, airless, pouches, stick packs, suppositories, capsules and unit-dose dispensers.
Supply chain: US and vetted global sources, alternate-vendor strategies to protect product launches.

Dietary Supplement Technologies

Atrium specializes in sublingual films, drinkable powders, and capsules, where bad-taste or ingredient stability would defeat regular formulations.

Fast-Dissolving ODF

High-loading up to 35% actives, taste-masking, high bioavailability.

Stick Packs

Label-friendly excipients, sugar-free systems, and stability systems.

Precise Capsules

Precise blending, consistent filling, strict quality control.

Suppository Delivery Systems

Lipid-base matrices, melting point tuning (33–37 °C), sedimentation control for suspended actives. Release profiling via in-vitro dissolution.

Unit-Dose

Leak-proof unit-dose packaging.

Automation

Fully-automated production lines.

Quality

Consistent & strict quality control.

This image shows a close-up view of modern automated production equipment operating within Atrium Scientific Group’s FDA-registered, cGMP-compliant manufacturing facility. Advanced automation systems support batch consistency, controlled processing parameters, and scalable production across dietary supplements, oral thin films, topical formulations, and specialty dosage formats. Integrated automation enhances manufacturing efficiency while maintaining strict quality and regulatory oversight.

How We Work
From Problem Statement to Launch at US Speed

Problem Framing (Week 0–1): Technical intake, target project summary, claims guardrails, and design for manufacturability (fill sizes, pack lines).

Rapid Prototyping (Weeks 1–6): Formulation sprints; build A/B variants internally around critical vectors – pH, rheology, stability, taste, performance panelist testing.

Analytical & Stress Testing (Weeks 4–8): Assay (titration / HPLC), rheometry (yield stress & thixotropy), accelerated stability (e.g., 50 °C), transport abuse (freeze-thaw), pH drifting, and packaging compatibility analysis (permeation, reaction, stability, etc.).

Scale-Up + IQ/OQ (Weeks 8–10): Pilot batches on coater/gel mixers, line trials on actual pouches/syringes/strips; set CQAs and in-process controls.

Launch (Weeks 10–16): Final specs, CoA, stability plan, artwork/label review; build safety & substantiation documentation.

Case Studies


Heat-Stable Professional Whitening Gel (No Cold Shipping Required)
A U.S. in-office whitening brand needed a high-potency peroxide gel that could withstand freight temperatures up to 50 °C without potency loss or phase separation. We engineered a water-based system using peroxide-compatible polymers and a radical-scavenger matrix to slow autocatalytic breakdown. The near-neutral pH improved patient comfort and minimized sensitivity. The result: <15% peroxide loss after 30 days at 50 °C, zero leakage, smooth non-drip chairside handling, and successful U.S. commercialization with repeat orders and a post-launch complaint rate below 0.3%.

High-Load Sublingual Film with Bitter Actives
A brand required a fast-dissolving oral thin film (ODF) delivering >35% active load while effectively masking strong bitter notes. We developed a sublingual film using taste-masking microencapsulation, an optimized PEG plasticizer system, and moisture-protective pouch packaging to preserve stability. The result: disintegration ≤40 seconds (USP <2040>), content uniformity CV ≤5%, and pouch residual moisture ≤3% at 6-month accelerated conditions. The product successfully scaled to continuous roll-to-roll manufacturing with >95% yield post die-cut.

Target Product Summary: claims, channel (professional/DTC/retail), pricing requirements     
Functional requirements:
actives, flavor, peroxide level (if any), film size / thickness
Performance targets:
viscosity, pH, dosage, taste
Packaging preference:
syringe/dual-chamber/strip/pouch/suppository
Timelines: prototype date, pilot, first PO

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Let’s Build Together

Based in the USA. Fast to sample. Built for scale.
We can start with a feasibility study or a full R&D program.
Email: info@atriumsci.com  |  Tel: (626) 380-5887